Endocrine Abstracts

Introduction: Vitamin D has a potentially beneficial role in insulin resistance, but there is a lack of evidence in elderly. We report preliminary results of an ongoing study that investigated the effect vitamin D replacement treatment (12 weeks) on insulin resistance and metabolic parameters in elderly people with normal glucose tolerance.Methods/design: The study’s eligibility criteria were body mass index <30.0 kg/m2, creatinine le...

Introduction: The aim of this study was to investigate whether monthly ibandronate improves hip bone mineral density (BMD) to the same degree as weekly risedronate in osteoporotic elderly.Material and methods: Eighty-one older adults with osteoporosis, age ranging from 65 to 95 years (mean: 77.5 years) were completed the study. Patients were treated either ibandronate 150 mg once monthly (n=56) and risedronate 35 mg once weekly (n=25). Chan...

Objective: Visfatin, a novel adipocytokine, is predominantly expressed in visceral fat and correlated with obesity. The pathophysiologic role of visfatin in metabolic syndrome (MS) is not clear. We aimed to investigate the relationship between plasma visfatin levels and components of MS, and also the effect of therapeutic lifestyle change (TLC) on these parameters.Design and methods: Nineteen patients (5 male, 14 female; mean age 51.0±9.3 years; bod...

Objective: The pleiotropic functions of statins are crucial in reducing cardiovascular events. There is controversy about their effects on insulin resistance. The aim of this study was to investigate the effect of Fluvastatin treatment on plasma adiponectin and insulin levels in a group of dyslipidemic population who had no confounding factors for insulin resistance such as diabetes or hypertension.Design and methods: Forty nine (27 male, 22 female; mean...